منابع مشابه
Pharmacogenomics approach in psychiatry disorders
Psychiatric disorders are important health issues in the world, and their management is facing some serious challenges. Drugs that are widely used in the treatment of psychiatric disorders, including antidepressants, antipsychotics, and mood stabilizers, are often associated with many side effects and are adequately effective only in a small proportion of patients. Many factors, including genet...
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Effect of a drug is not always uniform throughout the human population. Drugs working well in one patient population may not work well in another population. Furthermore, some drugs may show adverse reactions with or without intended effects. Some drugs may even fail to exert any effect. Such unpredictable drug effects are due to a generalized approach iadopted for drug development. Today's dru...
متن کاملSystems Pharmacogenomics-Bridging the Gap
Biological systems are quintessentially complex. Normal function requires the constant orchestration of numerous pathways on widely varying spatial and temporal scales. To understand such a complex system, data has been collected on the molecular, cellular, organ, and population scales and across various -omes such as the genome, proteome, and metabolome. Unfortunately, it is often the case tha...
متن کاملPharmacogenomics: A Promising Approach Towards Treatment of Autism
Autism spectrum disorders (ASDs) are among the most common neuropsychiatric disorders, with an estimated worldwide prevalence of 1%-2.6% [1-3]. The affected individuals display deficits in social communication, impaired language development, and the presence of highly restricted inter ests and/or stereotyped repetitive behaviours [1,2,4-6]. Although a wide variety of treatments have been used t...
متن کاملComparing Two Sports Injury Surveillance Systems: A Novel Systematic Approach
Purpose: The present study aimed to compare two sports injury surveillance systems per the sports injury recording system of the sports medicine federation. Methods: A sports injury surveillance system was implemented to collect injury data. Athletic trainers recorded athletes’ sports injuries in soccer, volleyball, handball, taekwondo, and wrestling for 6 months in their user account via a sm...
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ژورنال
عنوان ژورنال: Wiley Interdisciplinary Reviews: Systems Biology and Medicine
سال: 2010
ISSN: 1939-5094,1939-005X
DOI: 10.1002/wsbm.42